Tensile Properties

Tensile Properties of Randomly Oriented Collagen Gels of Varying Concentration 2 ABSTRACT Proteins, such as collagen, are commonly say-so biomaterials for subprogram in health check products. Examples include contrived skin, bone, tendon, and other body tissues. The addition of a protein coating on a biomaterial could provide beneficial molecular(a) and physical properties. Little precedent testing has been done to absorb the tensile properties of collagen gels, characteristics that go past help in the development of a novel polymer/collagen biomaterial. The get to of this investigation is to determine the flexile moduli, eventual(prenominal) hear, and other tensile properties of collagen hydrogels with concentrations variable from 5-7 mg/mL. Collagen gel precedents will be tested use a uniaxial test syllabus on an MTS 858 Mini Bionix II test frame. Gels were made on ice from collagen isolated from rat-tail tendons and change state in 0.02M acetic acid. The col lagen was brought to physiological osmolarity using NaHCO3, 10x alpha-MEM, and Hepes. The resulting mixture was equalized at a pH of 7.4 using NaOH and diluted to its final book of account using H20. Gels were formed into a standard testing specimen by pouring the gel mixture into a silicone polymer mold and allowing it to solidify by warming to physiological temperature.

Gels were consequently subjected to uniaxial tension until failure at two independent strain rates to measure elastic modulus, ultimate stress, and other properties. Results indicated a marked variability in both ultimate stress and elastic modulus over the dress of concentrations used. Ultimate strength value ranged from .317 kPa to 1.85 kPa and elastic modulu! s from 10.392 Pa to 39.867 Pa over the three opposite concentrations. Key Terms: automatonlike testing, biomaterials, tendon, viscoelasticity, collagen, hydrogel 3 BACKGROUND T and m he tensile properties of connective tissues in the dismal body depend on their composition icrostructural organization of their material...If you mobilize for to get a full essay, order it on our website: OrderEssay.net

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