Jacek Skowronski Jacek Skowronski researches immunodeficiency viruses. He studies human immunodeficiency viruses, jazz as HIV, and simian immunodeficiency viruses, love as SIV. Particularly, he studies the viral protein Nef. This protein plays an important role in the initiation of AIDS. T lymphocytes, the tuck in cells that be worn-out in AIDS, are cultured to field of honor the affects the viruses have on them. The results showed that Nef fragmentizes the T cell receptor (TCR). It changes the normal of major histocompatibility complex I molecules, known as MHC I, a condition of compatibility between tissues of unlike objects and the tissues of the soundbox receiving it. This disruption is probably to be involved in the baulk of host insubordinate responses, whether it be human or simian. The haphazardness is qualifyd as AIDS. To field of honor the function of Nef, he uses inheritable molecules to signalize the cells involved in affecting the T lymphocyte.
He as well as studies SIV-infected monkeys to find the importance the Nef and T lymphocyte interactions for AIDS. He tied(p) tries to characterize Nef proteins by isolating them this instant from HIV-infected people. Results from his studies will incite in possible drugs that can disrupt the Nef functions and prevent AIDS. If you require to descend a full essay, hostelry it on our website:
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